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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦2.35%⁩, the S&P 500 down ⁦3.15%⁩, and the Nasdaq Composite down ⁦4.29%⁩. Market breadth is negative, with 4,389 stocks declining versus 726 advancing, pointing to a broadly bearish bias.

Dow Jones
52,103.4
Change
-1,252.72-2.35%
S&P 500
7,446.22
Change
-242.4-3.15%
Nasdaq Composite
24,631.986
Change
-1,104.527-4.29%
24H Gainers
726
24H Losers
4,389

52 Week Gainers

#Stock52 Week Range
4851Skye Bioscience, Inc.SKYE$1.14-1.75%7.72K$5.04M$1.11 - $12.800.00%
4852Twin Vee PowerCats CoVEEE$8.31-5.57%7.84K$4.86M$4.16 - $127.650.00%
4853Virax Biolabs Group LimitedVRAX$1.19+0.83%3.36M$948.36K$1.04 - $21.750.00%
4854SuperX AI Technology LimitedSUPX$4.72-1.26%196.23K$207.61M$4.11 - $53.360.00%
4855Worksport, LtdWKSP$0.27-11.75%236.90K$5.38M$0.26 - $3.130.01%
4856ICZOOM Group Inc.IZM$0.65-4.11%30.08K$1.07M$0.65 - $13.650.00%
4857Moolec Science SAMLEC$0.85-38.39%102.66K$617.20K$0.80 - $23.220.00%
4858Sports Entertainment Gaming Global CorporationSEGG$1.83+5.45%468.11K$6.23M$1.12 - $32.550.00%
4859authID Inc.AUID$0.22-9.97%196.76K$3.63M$0.21 - $2.820.00%
4860Autonomix Medical, Inc.AMIX$1.59-4.22%24.39K$3.12M$1.58 - $32.550.00%
4861Black Titan CorporationBTTC$0.29-7.42%64.73K$4.68M$0.29 - $10.050.00%
4862Scilex Holding CompanySCLX$1.65-7.65%34.34K$14.01M$1.65 - $27.000.00%
4863Linkhome Holdings Inc.LHAI$0.91-5.23%74.73K$15.09M$0.53 - $15.660.00%
4864Merlin, Inc.MRLN$0.79-13.45%1.33M$95.30M$0.74 - $17.000.00%
4865Magic Empire Global LimitedMEGL$0.12-20.34%888.39K$10.74M$0.11 - $1.540.00%
4866Momentus Inc.MNTS$1.66-9.41%864.74K$36.46M$1.60 - $22.200.00%
4867CalciMedica, Inc.CALC$1.27-10.95%14.22K$8.67M$1.00 - $36.000.00%
4868Vertical Aerospace Ltd.EVTL$0.37-7.38%1.94M$64.05M$0.34 - $7.330.00%
4869Polar Power, Inc.POLA$0.33-8.89%275.49K$1.41M$0.27 - $4.000.00%
4870Golden Sun Technology Group LimitedGSUN$0.18-2.00%209.24K$1.72M$0.17 - $2.300.00%
4871Smart Logistics Global LimitedSLGB$0.19-13.57%368.90K$13.98M$0.17 - $4.220.00%
4872My Size, Inc.MYSZ$0.78-5.95%18.42K$922.56K$0.75 - $9.760.00%
4873YYForce Inc.YFOR$0.12-7.81%1.26M$924.73K$0.11 - $2.050.00%
4874Evolution Metals & Technologies Corp.EMAT$1.77-3.51%318.61K$1.11B$1.28 - $24.090.00%
4875Real Messenger CorporationRMSG$0.17-11.05%68.96K$2.90M$0.15 - $3.900.00%
4876Senti Biosciences Holdings, Inc.SNTI$0.16-8.04%145.06K$7.23M$0.15 - $2.880.00%
4877Antelope Enterprise Holdings LimitedAEHL$13.19+125.68%13.81M$217.10M$2.98 - $379.200.00%
4878Cadrenal Therapeutics, Inc.CVKD$1.05-4.25%25.07K$3.74M$0.82 - $13.110.00%
4879Accuray IncorporatedARAY$0.12-21.26%1.51M$14.23M$0.11 - $1.460.00%
4880SANUWAVE Health, Inc.SNWV$2.19-58.64%601.95K$18.88M$2.13 - $36.200.00%
4881Bluejay Diagnostics, Inc.BJDX$2.27+0.67%34.23K$10.12M$1.84 - $28.320.00%
4882Enhanced Group Inc.ENHA$7.93+15.33%291.53K$100.15M$6.30 - $101.700.00%
4883bioAffinity Technologies, Inc.BIAF$2.66-10.24%53.43K$3.10M$2.57 - $80.700.00%
4884Youxin Technology LtdYAAS$0.74-0.68%3.69K$5.04M$0.70 - $12.850.00%
4885Mobix Labs, Inc.MOBX$0.56-9.02%1.07M$10.11M$0.54 - $13.300.00%
4886HUHUTECH International Group Inc.HUHU$0.71+27.24%8.92M$18.08M$0.32 - $12.200.00%
4887Quince Therapeutics, Inc.QNCX$31.61+6.05%137.08K$32.15M$15.10 - $909.980.00%
4888Murano Global Investments PLCMRNO$0.20-13.55%265.03K$16.18M$0.18 - $2.910.00%
4889Strata Skin Sciences, Inc.SSKN$0.000.00%0$0$0.00 - $1.750.00%
4890Femasys Inc.FEMY$1.32-7.99%41.63K$11.10M$1.29 - $22.200.00%
4891WeShop Holdings LimitedWSHP$2.39-5.88%53.44K$27.18M$2.17 - $250.000.00%
4892NANO-X IMAGING LTDNNOX$0.25-12.77%1.07M$19.92M$0.24 - $4.710.00%
4893Epsium Enterprise LimitedEPSM$0.83-1.89%23.59K$11.00M$0.73 - $12.350.00%
4894Mobile-health Network SolutionsMNDR$0.93-4.43%72.21K$823.72K$0.71 - $32.520.00%
4895NexGel, Inc.NXGL$3.61-3.99%6.40K$1.76M$3.00 - $53.600.00%
4896Callan JMB Inc.CJMB$0.30-14.14%400.08K$2.46M$0.26 - $5.610.00%
4897CDT Environmental Technology Investment Holdings LimitedCDTG$0.94-5.40%19.98K$2.85M$0.73 - $16.230.00%
4898Kandal M Venture LimitedFMFC$3.17-9.84%44.07K$1.71M$3.15 - $46.800.00%
4899FingerMotion, Inc.FNGR$0.11-6.55%2.22M$9.83M$0.09 - $1.680.00%
4900Veritone, Inc.VERI$0.50-11.44%1.65M$50.81M$0.50 - $6.900.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Skye Bioscience, Inc. (SKYE) currently leads with a 52-week gain of 90.58% as of 2026-11-05 16:47 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.