Dow Jones
52,220.73
Change
-1,135.39-2.13%
52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.
Market Overview
U.S. stocks are broadly lower today, with the Dow Jones down 2.13%, the S&P 500 down 2.73%, and the Nasdaq Composite down 3.83%. Market breadth is negative, with 4,207 stocks declining versus 908 advancing, pointing to a broadly bearish bias.
S&P 500
7,479.01
Change
-209.61-2.73%
Nasdaq Composite
24,750.424
Change
-986.089-3.83%
24H Gainers
908
24H Losers
4,207
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 4801 | Lyra Therapeutics, Inc.LYRA | $0.00 | 0.00% | 0 | $0 | $0.00 - $5.72 | 0.00% |
| 4802 | Eos Energy Enterprises, Inc.EOSE | $1.85 | -11.92% | 25.79M | $675.53M | $1.59 - $19.86 | 0.00% |
| 4803 | FibroBiologics, Inc.FBLG | $0.92 | -5.73% | 53.93K | $6.13M | $0.62 - $9.60 | 0.00% |
| 4804 | Taoping Inc. BVITAOP | $0.30 | -9.39% | 9.69K | $3.01M | $0.29 - $3.13 | 0.00% |
| 4805 | BrenX Ltd.BRNX | $0.44 | +1.46% | 30.60K | $854.72K | $0.41 - $10.36 | 0.00% |
| 4806 | Wheels Up Experience Inc.UP | $2.97 | -1.95% | 60.35K | $107.59M | $2.83 - $29.33 | 0.00% |
| 4807 | Roze AI Inc.RZAI | $2.69 | +15.74% | 535.30K | $320.51M | $2.29 - $35.55 | 0.00% |
| 4808 | Hain Celestial Group Inc.HAIN | $0.14 | -7.79% | 842.27K | $12.38M | $0.12 - $1.48 | 0.00% |
| 4809 | Atrium Therapeutics, Inc.RNA | $8.54 | -1.50% | 66.61K | $146.25M | $7.49 - $73.06 | 0.00% |
| 4810 | Stem, Inc.STEM | $2.40 | -16.32% | 285.48K | $23.06M | $2.15 - $22.12 | 0.00% |
| 4811 | E-Power Inc.EPOW | $3.59 | -1.64% | 654 | $8.35M | $2.60 - $35.25 | 0.00% |
| 4812 | Bioceres Crop Solutions Corp.BIOX | $0.21 | -15.81% | 65.03K | $13.66M | $0.19 - $2.03 | 0.00% |
| 4813 | Cardlytics, Inc.CDLX | $2.14 | -3.17% | 8.88K | $12.43M | $1.57 - $18.00 | 0.00% |
| 4814 | Decoy Therapeutics Inc.DCOY | $1.11 | -3.04% | 43.38K | $2.66M | $0.90 - $16.92 | 0.00% |
| 4815 | Helport AI LimitedHPAI | $0.32 | +0.73% | 2.33M | $12.20M | $0.23 - $4.57 | 0.00% |
| 4816 | Offerpad Solutions Inc.OPAD | $2.19 | -3.48% | 27.21K | $10.56M | $1.90 - $26.70 | 0.00% |
| 4817 | OpenWorld, Inc.OPNW | $0.66 | +7.74% | 249.43K | $8.95M | $0.65 - $8.18 | 0.00% |
| 4818 | WF International LimitedWXM | $1.39 | -30.85% | 64.34K | $4.33M | $1.39 - $19.10 | 0.00% |
| 4819 | Fusemachines Inc.FUSE | $0.31 | -13.37% | 108.14K | $12.40M | $0.26 - $3.67 | 0.00% |
| 4820 | NuScale Power CorporationSMR | $4.50 | -11.21% | 14.75M | $1.85B | $4.29 - $39.35 | 0.00% |
| 4821 | Innoviz Technologies Ltd.INVZ | $0.20 | -6.68% | 2.19M | $42.90M | $0.20 - $1.76 | 0.00% |
| 4822 | Aldeyra Therapeutics, Inc.ALDX | $0.58 | -11.71% | 230.85K | $34.81M | $0.53 - $5.93 | 0.00% |
| 4823 | Teads Holding CoTEAD | $0.17 | -36.76% | 587.09K | $16.87M | $0.17 - $1.48 | 0.00% |
| 4824 | Accendra Health, Inc.ACH | $0.27 | -1.49% | 910.71K | $20.86M | $0.19 - $4.69 | 0.00% |
| 4825 | Cycurion, Inc.CYCU | $2.31 | -5.51% | 50.52K | $7.48M | $2.00 - $56.59 | 0.00% |
| 4826 | Cheer Holding, Inc.CHR | $1.26 | -4.55% | 9.71K | $2.33M | $1.16 - $41.85 | 0.00% |
| 4827 | Traws Pharma, Inc.TRAW | $0.24 | -6.92% | 146.19K | $3.77M | $0.23 - $3.23 | 0.00% |
| 4828 | TEN Holdings, Inc.XHLD | $0.57 | -9.21% | 245.78K | $9.76M | $0.38 - $15.43 | 0.00% |
| 4829 | Microvast Holdings, Inc.MVST | $0.58 | -11.76% | 2.04M | $224.99M | $0.47 - $5.32 | 0.00% |
| 4830 | XCF Global, Inc.SAFX | $0.08 | -20.74% | 6.39M | $50.87M | $0.08 - $1.27 | 0.00% |
| 4831 | Mangoceuticals, Inc.MGRX | $0.20 | -10.19% | 330.94K | $4.23M | $0.16 - $2.41 | 0.00% |
| 4832 | Rain Enhancement Technologies Holdco, Inc.RAIN | $0.55 | -9.30% | 19.90K | $6.36M | $0.51 - $8.52 | 0.00% |
| 4833 | Q/C Technologies, Inc.QCLS | $0.34 | -9.39% | 232.94K | $2.74M | $0.32 - $8.17 | 0.05% |
| 4834 | LiqTech International, Inc.LIQT | $0.27 | -8.00% | 80.12K | $8.99M | $0.27 - $2.56 | 0.00% |
| 4835 | Deep Fission, Inc.FISN | $1.57 | -27.60% | 1.02M | $150.21M | $1.52 - $19.00 | 0.00% |
| 4836 | LiveWire Group, Inc.LVWR | $0.56 | -2.70% | 51.15K | $116.06M | $0.53 - $5.33 | 0.00% |
| 4837 | Aardvark Therapeutics, Inc.AARD | $1.12 | -8.73% | 173.46K | $26.26M | $0.93 - $16.60 | 0.00% |
| 4838 | Verra Mobility CorporationVRRM | $2.42 | -3.43% | 1.71M | $368.62M | $2.37 - $23.50 | 0.00% |
| 4839 | AIFU Inc.AIFU | $9.01 | -1.48% | 1.75K | $57.36M | $8.17 - $90.00 | 0.00% |
| 4840 | Newegg Commerce, Inc.NEGG | $9.07 | -8.09% | 26.53K | $190.23M | $8.86 - $96.29 | 0.00% |
| 4841 | Modular Medical, Inc.MODD | $1.52 | -8.68% | 40.26K | $14.43M | $1.52 - $18.00 | 0.00% |
| 4842 | MetaVia Inc.MTVA | $1.12 | -17.91% | 921.84K | $5.78M | $0.97 - $14.85 | 0.00% |
| 4843 | Baird Medical Investment Holdings LtdBDMD | $0.12 | +18.79% | 257.60M | $4.94M | $0.07 - $3.70 | 0.00% |
| 4844 | Jiuzi Holdings, Inc.JZXN | $1.05 | -1.40% | 42.46K | $1.40M | $0.75 - $11.10 | 0.00% |
| 4845 | eHealth, Inc.EHTH | $0.49 | -23.27% | 453.75K | $15.60M | $0.45 - $5.35 | 0.33% |
| 4846 | Click Holdings LimitedCLIK | $0.72 | -2.66% | 134.79K | $5.81M | $0.60 - $8.65 | 0.00% |
| 4847 | Acumen Pharmaceuticals, Inc.ABOS | $0.20 | -9.57% | 3.64M | $14.25M | $0.19 - $3.60 | 0.00% |
| 4848 | SunCar Technology Group Inc.SDA | $0.18 | -13.20% | 239.33K | $10.85M | $0.17 - $2.45 | 0.00% |
| 4849 | Sionna Therapeutics, Inc.SION | $3.37 | -8.04% | 335.73K | $168.64M | $3.36 - $54.97 | 0.00% |
| 4850 | Knightscope, Inc.KSCP | $0.42 | -7.35% | 555.82K | $9.87M | $0.42 - $5.96 | 0.00% |
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| Position types | Buy and hold | Buy and hold | Long, short, leveraged |
| Best for | Long-term investors seeking ownership and dividend income | Traders wanting round-the-clock access to stock exposure without holding shares | Active/short-term traders looking to speculate or hedge with leverage |
RealStocks
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Lyra Therapeutics, Inc. (LYRA) currently leads with a 52-week gain of 87.51% as of 2026-11-05 16:55 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.
Discover Top US Stocks
Apple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBV
Apple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBV
Nvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COST
Nvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COST
Microsoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVX
Microsoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVX
Alphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTR
Alphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTR
Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.