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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.23%⁩, the S&P 500 is ⁦-0.78%⁩, and the Nasdaq Composite is ⁦-1.75%⁩. Across individual stocks, 701 are advancing while 4,412 are declining, suggesting a mixed market tone.

Dow Jones
53,476.22
Change
+120.1+0.23%
S&P 500
7,628.62
Change
-60.0-0.78%
Nasdaq Composite
25,285.1
Change
-451.413-1.75%
24H Gainers
701
24H Losers
4,412

52 Week Gainers

#Stock52 Week Range
4951Aptevo Therapeutics Inc.APVO$1.23-16.79%130.70K$2.22M$1.13 - $28.080.00%
4952Singularity Future Technology LtdSGLY$0.42-11.87%90.65K$2.26M$0.30 - $14.280.00%
4953Innventure, Inc.INV$0.17-25.13%5.69M$14.58M$0.14 - $7.860.00%
4954Olenox Industries Inc.OLOX$0.68-5.56%106.00K$1.13M$0.60 - $21.900.00%
4955BNB Plus Corp.BNBX$0.16-58.08%4.55M$0$0.07 - $3.590.00%
4956Core AI Holdings, Inc.CHAI$0.17-7.92%81.05K$3.35M$0.17 - $4.050.00%
4957CCSC Technology International Holdings LimitedCCTG$0.28-0.14%89.45K$3.93M$0.17 - $16.900.00%
4958Future FinTech Group Inc.FTFT$3.83-4.77%120.05K$33.22M$1.22 - $97.270.00%
4959Ernexa Therapeutics Inc.ERNA$1.76-14.15%12.66K$2.87M$1.75 - $46.110.00%
4960Vivos Therapeutics, Inc.VVOS$0.10-7.62%279.48K$3.46M$0.10 - $2.720.00%
4961Robo.ai Inc.AIIO$0.41-20.02%592.77K$91.96M$0.40 - $20.600.00%
4962Liminatus Pharma, Inc.LIMN$2.73-2.30%98.27K$3.38M$2.40 - $141.500.00%
4963Vistagen Therapeutics, Inc.VTGN$0.17-8.57%706.09K$7.68M$0.17 - $5.140.00%
4964Children's Place, Inc.PLCE$0.32+27.55%68.54M$7.05M$0.20 - $9.560.00%
4965Artelo Biosciences, Inc.ARTL$2.14-2.64%34.91K$1.17M$2.05 - $179.190.00%
4966Jyong Biotech Ltd.MENS$1.67+1.89%21.50K$127.04M$1.43 - $43.780.00%
4967FiscalNote Holdings, Inc.NOTE$0.000.00%0$0$0.00 - $3.740.00%
4968Arcadia Biosciences, Inc.RKDA$0.15-9.54%131.83K$363.79K$0.11 - $4.180.00%
4969Tempest Therapeutics, Inc.TPST$0.40-13.66%206.31K$8.04M$0.39 - $10.330.00%
4970Solmate Infrastructure Public Limited CompanySLMT$3.01-6.00%40.26K$25.24M$2.79 - $85.310.00%
4971Getty Images Holdings, Inc.GETY$0.08-40.95%27.99M$0$0.00 - $3.210.00%
4972Boxlight CorporationBOXL$2.00-4.09%16.77K$1.68M$1.88 - $51.120.00%
4973Tenon Medical, Inc.TNON$1.66-12.30%126.52K$4.45M$1.66 - $45.500.00%
4974Veraxa Biotech AGVRXA$0.96+6.32%59.43K$145.65M$0.95 - $27.360.00%
4975Algorhythm Holdings, Inc.RIME$0.08-18.09%1.06M$1.33M$0.08 - $4.580.00%
4976Tianci International, Inc.CIIT$1.60-2.73%11.03K$1.55M$1.55 - $52.500.00%
4977CXApp Inc.CXAI$1.22-23.38%204.37K$2.86M$1.15 - $33.270.00%
4978Decent Holding Inc.DXST$1.05-1.87%14.36K$2.28M$1.01 - $62.000.00%
4979Nexalin Technology, Inc.NXL$1.44-9.43%10.26K$1.58M$1.41 - $43.500.00%
4980VS Media Holdings LimitedVSME$1.03+28.05%219.32K$4.69M$0.58 - $30.800.00%
4981Trident Digital Tech Holdings LtdTDTH$0.66-12.79%31.58K$18.95M$0.56 - $21.000.00%
4982Datavault AI Inc.DVLT$0.06-18.70%50.03M$52.99M$0.05 - $2.700.00%
49833 E Network Technology Group LtdMASK$1.83+5.18%3.21M$2.39M$1.50 - $66.530.00%
4984VenHub Global, Inc.VHUB$0.22-7.84%63.81K$22.16M$0.21 - $40.300.00%
4985Cable One, Inc.CABO$4.99-3.71%95.91K$28.28M$4.36 - $145.220.00%
4986Cloudastructure, Inc.CSAI$1.96-4.71%15.55K$1.70M$1.93 - $69.150.11%
4987EyePoint, Inc.EYPT$0.37-6.73%1.17M$32.24M$0.34 - $19.110.00%
4988Moleculin Biotech, Inc.MBRX$7.91-1.24%6.33K$8.48M$3.23 - $253.050.00%
4989GRI Bio, Inc.GRI$1.55+4.20%82.05K$3.39M$1.36 - $64.120.00%
4990Maison Solutions Inc.MSS$1.00-15.88%66.89K$811.35K$0.94 - $32.250.00%
4991Nocera, Inc.NCRA$1.35-6.31%6.40K$3.27M$1.30 - $46.800.00%
4992Agroz Inc.AGRZ$1.87-1.78%8.38K$2.31M$1.73 - $105.680.00%
4993Powell Max LimitedPMAX$0.73-35.05%804.16K$951.14K$0.45 - $33.500.00%
4994MDxHealth SAMDXH$0.15-6.84%551.50K$14.98M$0.14 - $4.830.00%
4995707 Cayman Holdings LimitedJEM$2.52-2.90%10.11K$1.67M$2.38 - $135.240.00%
4996IceCure Medical Ltd.ICCM$0.68-12.34%71.24K$2.31M$0.65 - $22.500.00%
4997Curis Inc.CRIS$0.89-19.81%9.68M$1.86M$0.33 - $29.810.00%
4998Triller Group Inc.ILLR$0.19-18.65%3.40M$0$0.01 - $7.960.00%
4999MKDWELL Tech Inc.MKDW$0.17+5.22%1.64M$5.81M$0.14 - $12.940.00%
5000iSpecimen Inc.ISPC$0.79-7.12%93.76K$1.99M$0.75 - $27.440.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Aptevo Therapeutics Inc. (APVO) currently leads with a 52-week gain of 95.24% as of 2026-11-05 16:35 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.