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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦2.39%⁩, the S&P 500 down ⁦3.20%⁩, and the Nasdaq Composite down ⁦4.34%⁩. Market breadth is negative, with 4,488 stocks declining versus 627 advancing, pointing to a broadly bearish bias.

Dow Jones
52,079.35
Change
-1,276.77-2.39%
S&P 500
7,442.66
Change
-245.96-3.20%
Nasdaq Composite
24,620.543
Change
-1,115.97-4.34%
24H Gainers
627
24H Losers
4,488

52 Week Gainers

#Stock52 Week Range
4601Imunon, Inc.IMNN$0.90-3.55%54.70K$5.03M$0.81 - $4.380.00%
4602Tenax Therapeutics, Inc.TENX$1.58-12.43%1.18M$59.32M$1.31 - $19.400.00%
4603DocGo Inc.DCGO$0.24-7.77%163.70K$23.84M$0.21 - $1.170.00%
4604Prairie Operating CoPROP$0.41+2.01%262.95K$45.91M$0.32 - $2.550.00%
4605Armlogi Holding Corp.BTOC$1.97-7.46%13.03K$5.60M$1.97 - $11.490.00%
4606Sow Good Inc.SOWG$2.33+9.62%12.84K$46.93M$1.04 - $15.900.00%
4607NET Power Inc.NPWR$0.79-5.31%374.98K$69.72M$0.77 - $3.710.00%
4608Research Frontiers Inc.REFR$0.37-3.08%27.05K$13.04M$0.33 - $2.100.00%
4609Rapid Micro Biosystems, Inc.RPID$0.63-9.13%97.17K$28.63M$0.63 - $4.940.00%
4610Advanced Biomed Inc.ADVB$1.93-8.77%16.42K$3.20M$1.81 - $24.230.00%
4611MacKenzie Realty Capital, Inc.MKZR$1.07+1.92%5.50K$2.97M$0.83 - $5.220.00%
4612Swarmer, Inc.SWMR$6.75-13.20%498.40K$130.36M$6.53 - $83.300.00%
4613Processa Pharmaceuticals, Inc.PCSA$1.85-5.94%16.03K$5.17M$1.04 - $8.990.00%
4614Bit Digital, Inc.BTBT$0.71-14.85%12.94M$256.77M$0.69 - $3.330.00%
4615Iveda Solutions, Inc.IVDA$0.20-13.19%237.67K$2.55M$0.19 - $1.520.00%
4616Longeveron Inc.LGVN$1.65-4.49%19.54K$5.03M$1.31 - $12.300.00%
4617Pulsenmore Ltd.PLSM$1.59-0.64%13.21K$10.66M$1.48 - $12.970.00%
4618Intelligent Group LimitedINTJ$2.50-16.50%3.85K$4.77M$2.38 - $12.520.00%
4619One and One Green Technologies. Inc.YDDL$0.99-2.67%27.77K$58.83M$0.91 - $16.230.00%
4620Alpha Compute Corp.ALP$3.01-6.23%16.41K$4.67M$2.78 - $27.900.00%
4621Fervo Energy CompanyFRVO$7.84-12.58%4.23M$2.43B$7.72 - $42.650.00%
4622Akebia Therapeutics, Inc.AKBA$0.45-34.98%9.90M$125.81M$0.45 - $2.130.00%
4623Rail Vision Ltd.RVSN$2.65-7.02%31.47K$5.82M$2.60 - $13.540.00%
4624Tevogen Inc.TVGN$5.62-2.09%727$88.36M$3.64 - $32.500.00%
4625Ohmyhome LimitedOMH$13.11-12.54%8.62M$6.22M$2.05 - $109.500.00%
4626Tilray Brands, Inc.TLRY$2.73-7.77%3.77M$402.87M$2.48 - $15.700.00%
4627First Breach Inc.FBDT$0.88-0.24%78.44K$52.44M$0.61 - $12.000.00%
4628Intelligent Bio Solutions Inc.INBS$1.74+1.99%17.24K$5.78M$1.35 - $24.900.00%
4629Rani Therapeutics Holdings, Inc.RANI$0.53-7.38%405.04K$61.06M$0.52 - $2.630.00%
4630Neonode Inc.NEON$0.59-11.89%57.96K$9.95M$0.57 - $2.890.00%
4631Globavend Holdings LimitedGVH$1.01+6.73%39.58K$4.37M$0.77 - $6.460.00%
4632SharonAI Holdings, Inc.SHAZ$19.94-18.96%828.15K$711.24M$16.55 - $97.480.00%
4633Xanadu Quantum Technologies LimitedXNDU$2.40-8.78%2.48M$791.42M$2.35 - $42.440.00%
4634DarioHealth Corp.DRIO$2.82-3.70%39.69K$27.67M$2.81 - $14.770.00%
4635Australian Oilseeds Holdings LimitedCOOT$0.28-1.43%16.70K$7.70M$0.27 - $1.530.00%
4636PowerCompute, Inc.PWCM$0.46-8.15%136.83K$1.15M$0.43 - $2.550.00%
4637Richtech Robotics Inc.RR$0.83-7.33%3.31M$153.69M$0.80 - $5.600.00%
4638Enovix CorporationENVX$2.33-15.59%5.78M$510.22M$2.19 - $11.650.00%
4639Intensity Therapeutics, Inc.INTS$2.93-7.41%28.04K$9.55M$2.85 - $15.750.00%
4640NeuroOne Medical Technologies CorporationNMTC$0.90-5.36%20.19K$8.19M$0.77 - $6.120.00%
4641Tvardi Therapeutics, Inc.TVRD$0.86+1.13%105.40K$11.51M$0.77 - $5.690.00%
4642ASP Isotopes Inc.ASPI$1.72-10.99%2.93M$262.93M$1.66 - $9.380.00%
4643Tantech Holdings LtdTANH$11.87+0.76%37.71K$8.54M$8.01 - $63.000.00%
4644Haoxin Holdings LimitedHXHX$0.15-27.41%382.08K$1.52M$0.13 - $1.470.00%
4645Byrna Technologies, Inc.BYRN$3.73-9.86%185.85K$87.42M$3.17 - $20.690.00%
4646Organogenesis Holdings Inc.ORGO$0.80-6.80%291.60K$103.07M$0.73 - $7.080.00%
4647Incannex Healthcare LimitedIXHL$2.28-9.24%79.79K$28.58M$2.17 - $14.910.00%
4648Serve Robotics Inc.SERV$2.35-12.08%2.60M$203.68M$2.26 - $16.080.00%
4649Hang Feng Technology Innovation Co., Ltd.FOFO$1.77+6.95%7.75K$13.30M$1.58 - $14.930.00%
4650Yueda Digital HoldingYDKG$1.02+7.62%216.86K$4.92M$0.73 - $5.400.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Imunon, Inc. (IMNN) currently leads with a 52-week gain of 77.58% as of 2026-11-05 17:20 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.