52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview
U.S. stocks are broadly lower today, with the Dow Jones down 2.62%, the S&P 500 down 3.45%, and the Nasdaq Composite down 4.65%. Market breadth is negative, with 4,530 stocks declining versus 585 advancing, pointing to a broadly bearish bias.
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 4551 | Gaxos.ai Inc.GXAI | $0.37 | -16.91% | 510.30K | $4.12M | $0.35 - $2.63 | 0.00% |
| 4552 | Tenaya Therapeutics, Inc.TNYA | $0.34 | -7.81% | 3.89M | $77.50M | $0.34 - $1.56 | 0.00% |
| 4553 | Caring Brands, Inc.CABR | $0.75 | -6.67% | 132.51K | $10.89M | $0.71 - $4.39 | 0.00% |
| 4554 | OneMedNet Corp.ONMD | $4.28 | -6.50% | 11.61K | $25.34M | $3.61 - $23.00 | 0.00% |
| 4555 | NextTrip, Inc.NTRP | $1.10 | -4.43% | 11.85K | $16.74M | $0.90 - $4.80 | 0.00% |
| 4556 | Heron Therapeutics, Inc.HRTX | $0.27 | -9.31% | 760.17K | $51.26M | $0.26 - $1.57 | 0.00% |
| 4557 | Dermata Therapeutics, Inc.DRMA | $0.77 | -9.29% | 32.23K | $3.82M | $0.60 - $4.66 | 0.00% |
| 4558 | AETHLON MEDICAL INC.AEMD | $5.48 | -4.20% | 7.79K | $3.90M | $1.41 - $25.66 | 0.00% |
| 4559 | Alight, Inc.ALIT | $12.14 | -6.82% | 421.29K | $320.71M | $7.93 - $57.00 | 0.16% |
| 4560 | Solid Power, Inc.SLDP | $2.06 | -7.56% | 3.08M | $468.91M | $1.91 - $8.86 | 0.00% |
| 4561 | Lexaria Bioscience Corp.LEXX | $3.91 | -3.93% | 19.28K | $8.24M | $2.43 - $21.60 | 0.00% |
| 4562 | DNA X, Inc.SONM | $2.79 | -2.33% | 25.44K | $4.14M | $2.21 - $11.90 | 0.00% |
| 4563 | Aptera Motors Corp.SEV | $2.02 | -2.40% | 107.79K | $75.32M | $1.29 - $8.80 | 0.00% |
| 4564 | Jasper Therapeutics, Inc.JSPR | $0.47 | -7.51% | 320.77K | $15.61M | $0.32 - $2.42 | 0.00% |
| 4565 | APOLLO COMMERCIAL REAL ESTATE FINANCE, INC.ARI | $2.38 | -4.78% | 1.67M | $306.58M | $2.28 - $11.24 | 0.49% |
| 4566 | OBOOK Holdings Inc.OWLS | $2.31 | +2.22% | 10.71K | $203.17M | $1.36 - $9.75 | 0.00% |
| 4567 | Heartbeam, Inc.BEAT | $0.40 | -6.30% | 368.74K | $22.26M | $0.35 - $4.00 | 0.00% |
| 4568 | Foremost Clean Energy LtdFMST | $0.67 | -9.12% | 118.64K | $10.90M | $0.42 - $3.49 | 0.00% |
| 4569 | Bitdeer Technologies GroupBTDR | $5.28 | -21.06% | 9.44M | $1.44B | $5.03 - $23.30 | 0.00% |
| 4570 | Vivid Seats Inc.SEAT | $2.85 | +1.32% | 14.97K | $32.00M | $2.03 - $12.72 | 0.00% |
| 4571 | enCore Energy Corp.EU | $0.63 | -11.84% | 1.69M | $123.70M | $0.63 - $3.67 | 0.00% |
| 4572 | IREN LimitedIREN | $18.18 | -16.77% | 62.72M | $7.36B | $17.18 - $76.87 | 0.00% |
| 4573 | BitGo Holdings, Inc.BTGO | $4.39 | -19.00% | 976.67K | $603.01M | $4.38 - $24.50 | 0.00% |
| 4574 | Ambitions Enterprise Management Co. L.L.CAHMA | $1.11 | +1.83% | 20.35K | $31.81M | $0.76 - $39.50 | 0.00% |
| 4575 | QuantumScape CorporationQS | $4.04 | -8.80% | 8.81M | $2.38B | $3.80 - $17.71 | 0.00% |
| 4576 | Arbe Robotics Ltd.ARBE | $0.41 | +1.02% | 836.05K | $52.58M | $0.39 - $1.94 | 0.00% |
| 4577 | Investcorp Credit Management BDC, Inc.ICMB | $0.65 | -4.28% | 9.71K | $9.35M | $0.62 - $3.12 | 0.43% |
| 4578 | Circle8 Group, Inc.CIRC | $0.19 | -14.05% | 230.90K | $22.79M | $0.19 - $0.98 | 0.00% |
| 4579 | Quantum Biopharma LtdQNTM | $2.11 | -5.88% | 46.24K | $8.05M | $2.05 - $12.42 | 0.00% |
| 4580 | SS Innovations International Inc.SSII | $1.73 | -23.35% | 106.21K | $346.07M | $1.64 - $7.76 | 0.00% |
| 4581 | Cheche Group Inc.CCG | $8.14 | +4.00% | 4.57K | $16.08M | $4.11 - $36.75 | 0.00% |
| 4582 | BTQ Technologies Corp.BTQ | $1.70 | -12.11% | 1.67M | $253.86M | $1.66 - $7.92 | 0.00% |
| 4583 | ZeroStack Corp.ZSTK | $2.74 | -0.90% | 15.77K | $59.79M | $1.32 - $15.04 | 0.00% |
| 4584 | EUDA Health Holdings LimitedEUDA | $14.78 | -1.00% | 12.19K | $44.26M | $5.26 - $71.20 | 0.00% |
| 4585 | Filana Therapeutics, Inc.FLNA | $0.48 | -12.59% | 385.21K | $23.33M | $0.48 - $2.27 | 0.00% |
| 4586 | Tactical Resources Corp.TREO | $1.65 | +2.04% | 13.34K | $23.82M | $1.40 - $9.20 | 0.00% |
| 4587 | Genelux CorporationGNLX | $1.79 | -8.16% | 151.33K | $81.22M | $1.75 - $8.54 | 0.00% |
| 4588 | WEBUY GLOBAL LTDWBUY | $0.52 | +0.40% | 21.27K | $2.72M | $0.49 - $4.96 | 0.00% |
| 4589 | Pasqal Holding SAPSQL | $4.36 | -13.99% | 477.37K | $1.12B | $4.33 - $24.69 | 0.00% |
| 4590 | Exicure, Inc.XCUR | $0.94 | +0.54% | 2.55K | $6.12M | $0.88 - $9.48 | 0.00% |
| 4591 | Rocket One Inc.RKTO | $0.39 | -12.91% | 219.88K | $9.64M | $0.39 - $2.45 | 0.00% |
| 4592 | NervGen Pharma Corp.NGEN | $1.35 | +1.85% | 184.69K | $109.17M | $1.28 - $6.30 | 0.00% |
| 4593 | Atlas Critical Minerals CorporationATCX | $2.00 | -4.95% | 4.93K | $8.82M | $1.85 - $14.01 | 0.00% |
| 4594 | Cipher Digital Inc.CIFR | $5.60 | -15.77% | 42.48M | $2.32B | $5.08 - $30.14 | 0.00% |
| 4595 | Creative Medical Technology Holdings, Inc.CELZ | $0.63 | -9.43% | 66.35K | $4.18M | $0.60 - $4.72 | 0.00% |
| 4596 | Odyssey Marine Exploration, Inc.OMEX | $11.04 | -2.52% | 20.63K | $28.41M | $9.59 - $66.75 | 0.00% |
| 4597 | loanDepot, Inc.LDI | $0.63 | -6.34% | 1.36M | $145.51M | $0.48 - $3.24 | 0.00% |
| 4598 | Z Squared Inc.ZSQR | $3.42 | -4.96% | 168.91K | $181.00M | $2.11 - $18.80 | 0.00% |
| 4599 | Aclarion, Inc.ACON | $1.69 | -2.71% | 6.55K | $4.86M | $1.69 - $9.36 | 0.00% |
| 4600 | Nano Nuclear Energy Inc.NNE | $9.75 | -11.60% | 2.11M | $523.56M | $9.31 - $45.46 | 0.00% |
Trade U.S. stocks Your Way on MEXC
| RealStocks | Tokenized Stocks | Stock Futures | |
|---|---|---|---|
| What it is | RealStocks — real shares of U.S.-listed companies | Blockchain-based tokens linked to U.S. stocks/ETFs | USDT-margined futures on U.S. stock price movements |
| Ownership | Yes — actual shares | No — synthetic exposure only | No — derivative exposure only |
| Shareholder rights | Yes (e.g. dividends) | No | No |
| Trading hours | U.S. market sessions (pre-market, regular, after-hours, overnight) | 24/7 | Up to 24/7 (supported pairs) |
| Position types | Buy and hold | Buy and hold | Long, short, leveraged |
| Best for | Long-term investors seeking ownership and dividend income | Traders wanting round-the-clock access to stock exposure without holding shares | Active/short-term traders looking to speculate or hedge with leverage |
Why Trade U.S. stocks on MEXC?
RealStocks, Real Ownership
Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.
7,000+ U.S. stocks & ETFs
Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.
Seamless USDT-to-Stock Access
Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.
Lower-Cost Stock Trading
Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.
Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
How is the 52-week gain calculated?
Which stock has gained the most over 52 weeks?
Why use a 52-week stock performance ranking?
Does strong 52-week performance guarantee future gains?
How is this different from the daily Top Gainers list?
Discover Top US Stocks
Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.






.b39e813829fa.png)

.b39e815d234d.png)
.b39e81c62f33.png)
.b39e81f7d220.png)
