Buy Crypto
Markets
Spot
FuturesBTC
Earn
Event Center
Rewards Hub
More

52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+3.03%⁩, the S&P 500 is ⁦+1.58%⁩, and the Nasdaq Composite is ⁦+1.44%⁩. Across individual stocks, 546 are advancing while 4,504 are declining, suggesting a mixed market tone.

Dow Jones
53,356.12
Change
+1,569.4+3.03%
S&P 500
7,688.62
Change
+119.7+1.58%
Nasdaq Composite
25,736.513
Change
+364.504+1.44%
24H Gainers
546
24H Losers
4,504

52 Week Gainers

#Stock52 Week Range
5101Onconetix, Inc.ONCO$0.59-9.28%703.85K$3.48M$0.34 - $161.000.00%
5102Lucas GC LimitedLGCL$1.25-6.20%4.70K$1.67M$1.23 - $423.750.00%
5103Kaixin HoldingsKXIN$2.48+9.42%1.97M$49.64M$0.54 - $832.500.00%
5104SmartKem, Inc.SMTK$0.28-5.00%45.91K$291.06K$0.23 - $100.000.00%
5105TruGolf Holdings, Inc.TRUG$0.57-4.88%69.41K$868.80K$0.57 - $217.000.00%
5106Stardust Power Inc.SDST$0.01-30.11%147.33M$0$0.00 - $4.870.00%
5107Recon Technology, LtdRCON$0.85+5.83%63.18K$24.96M$0.81 - $361.980.00%
5108Next Technology Holding Inc.NXTT$4.70-3.93%8.69K$6.92M$4.51 - $1,949.000.00%
5109Ridgetech, Inc.RDGT$0.78+1.31%5.28K$2.81M$0.67 - $760.500.00%
5110Intercont (Cayman) LimitedNCT$1.43-0.68%271.81K$1.45M$1.22 - $706.250.00%
5111Our Bond, Inc.OBAI$1.72-6.54%26.87K$3.75M$1.70 - $770.000.00%
5112Clearmind Medicine Inc.CMND$5.80-2.03%2.89K$2.95M$5.25 - $2,624.000.00%
5113Functional Brands, Inc.MEHA$0.00-55.31%0$0$0.00 - $8.000.00%
5114Jet.AI Inc.JTAI$0.87-12.99%63.68K$1.24M$0.80 - $452.000.00%
5115Solowin HoldingsAXG$1.44-16.37%186.19K$1.94M$1.38 - $950.000.00%
5116ReTo Eco-Solutions, Inc.RETO$3.64-8.54%44.44K$1.23M$3.00 - $3,336.000.00%
5117Digital Brands Group, Inc.DBGI$0.56-4.43%30.65K$522.77K$0.49 - $720.000.00%
5118Faraday Future Intelligent Electric Inc.FFAI$0.33-28.32%1.66M$2.04M$0.29 - $199.500.00%
5119Robin Energy LtdRBNE$0.14-3.45%13.54M$201.18K$0.12 - $92.250.00%
5120PMGC Holdings Inc.ELAB$1.82-4.21%130.29K$1.47M$1.73 - $1,471.200.00%
5121Zeta Network GroupZNB$1.08+76.85%33.42M$5.43M$0.35 - $976.000.00%
5122EZGO Technologies Ltd.EZGO$1.97+0.87%69.98K$4.55M$0.64 - $3,296.250.00%
5123Hitek Global Inc.HKIT$2.51+5.81%12.71M$2.00M$2.13 - $5,225.000.00%
5124GD Culture Group LimitedGDC$1.14-9.27%89.07K$4.72M$1.05 - $2,044.970.00%
5125Healthcare Triangle, Inc.HCTI$3.76-10.82%29.33K$3.34M$3.67 - $3,390.000.00%
5126Vision Marine Technologies Inc.VMAR$5.44-2.48%7.25K$3.55M$5.16 - $6,320.000.00%
5127SHF Holdings, Inc.SHFS$0.03-10.69%50.73M$47.48K$0.03 - $31.290.00%
5128Zhongchao Inc.ZCMD$0.96-3.38%23.79K$4.07M$0.87 - $1,443.360.00%
5129Edible Garden AG IncorporatedEDBL$0.69-7.86%119.69K$954.14K$0.67 - $751.410.00%
5130Oriental Culture Holding LTDOCG$1.61-0.49%10.45K$3.12M$1.37 - $12,731.400.00%
5131Lion Group Holding Ltd. AmericanLGHL$1.48-24.54%55.05K$38.14K$1.34 - $2,183.920.00%
5132Republic Power Group LimitedRPGL$13.74-5.04%9.04K$14.34M$6.00 - $34,432.000.00%
5133Mingteng International Corporation Inc.MTEN$0.33-31.93%160.85K$3.82M$0.28 - $582.000.00%
5134AiRWA Inc.YYAI$0.89-2.95%147.66K$4.05M$0.64 - $1,536.000.00%
5135JIADE LIMITEDJDZG$0.34+39.72%26.06M$2.88M$0.29 - $1,014.980.00%
5136Digital Currency X Technology Inc.DCX$1.05-3.21%23.48K$2.48M$1.04 - $1,603.200.00%
5137Haoxi Health Technology LimitedHAO$1.86-2.77%9.38K$1.11M$1.60 - $4,352.000.00%
5138GMEX ROBOTICS CORPORATIONGMEX$0.44-14.20%57.33K$659.89K$0.44 - $961.630.00%
5139Jaguar Health, Inc.JAGX$0.38-25.22%701.67K$887.53K$0.37 - $1,102.500.00%
5140SMX (Security Matters) Public Limited CompanySMX$1.33+8.47%1.12M$1.45M$1.15 - $109,340.800.00%
5141Profusa, Inc.PFSA$0.57-6.89%61.13K$394.28K$0.56 - $1,722.000.00%
5142KIDZ AI Inc.KIDZ$1.17-15.22%41.55K$1.23M$1.15 - $5,217.000.00%
5143VCI Global LimitedVCIG$6.03+7.17%115.22K$941.79K$2.70 - $35,316.000.00%
5144Elong Power Holding LimitedELPW$3.38+41.83%54.21M$2.56M$2.20 - $54,972.000.00%
5145La Rosa Holding Corp.LRHC$0.77-12.75%8.58M$431.73K$0.73 - $3,840.000.00%
5146Founder Group LimitedFGL$1.27-6.43%15.98K$15.58K$1.21 - $5,530.000.00%
5147NewGenIvf Group LimitedNIVF$0.50-27.78%157.39K$608.91K$0.47 - $10,507.970.00%
514822nd Century Group Inc.XXII$2.00-11.74%242.94K$1.03M$0.55 - $23,838.000.00%
5149Li Bang International Corporation Inc.LBGJ$1.68-7.13%18.98K$988.55K$1.29 - $25,400.000.00%
5150iPower, Inc.IPW$1.35-9.67%35.77K$722.10K$1.33 - $12,407.040.00%

Anthropic (PRE): Win NVIDIA H200

Claim PRE points for guaranteed prizes up to $3K

Anthropic (PRE): Win NVIDIA H200

Trade U.S. stocks Your Way on MEXC

RealStocksTokenized StocksStock Futures
What it isRealStocks — real shares of U.S.-listed companiesBlockchain-based tokens linked to U.S. stocks/ETFsUSDT-margined futures on U.S. stock price movements
OwnershipYes — actual sharesNo — synthetic exposure onlyNo — derivative exposure only
Shareholder rightsYes (e.g. dividends)NoNo
Trading hoursU.S. market sessions (pre-market, regular, after-hours, overnight)24/7Up to 24/7 (supported pairs)
Position typesBuy and holdBuy and holdLong, short, leveraged
Best forLong-term investors seeking ownership and dividend incomeTraders wanting round-the-clock access to stock exposure without holding sharesActive/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Onconetix, Inc. (ONCO) currently leads with a 52-week gain of 99.61% as of 2026-11-05 16:35 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.