Buy Crypto
Markets
Spot
FuturesBTC
Earn
Event Center
Rewards Hub
More

52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦2.83%⁩, the S&P 500 down ⁦3.51%⁩, and the Nasdaq Composite down ⁦4.45%⁩. Market breadth is negative, with 4,646 stocks declining versus 469 advancing, pointing to a broadly bearish bias.

Dow Jones
51,842.16
Change
-1,513.96-2.83%
S&P 500
7,418.49
Change
-270.13-3.51%
Nasdaq Composite
24,591.04
Change
-1,145.473-4.45%
24H Gainers
469
24H Losers
4,646

52 Week Losers

#Stock52 Week Range
2201Lyell Immunopharma, Inc.LYEL$14.77-3.69%470.30K$361.93M$7.20 - $45.000.00%
2202Autodesk Inc.ADSK$268.85-0.70%2.29M$56.19B$185.50 - $320.000.00%
2203Mount Logan Capital Inc.MLCIL$21.690.00%1.01K$0$20.05 - $24.500.00%
2204AppFolio, Inc.APPF$230.06-2.45%340.45K$5.55B$142.56 - $263.400.00%
2205Deswell Industries Inc.DSWL$3.00+3.38%9.88K$47.58M$2.80 - $4.060.00%
2206Omega Flex, Inc.OFLX$24.13-7.61%25.20K$243.53M$23.93 - $37.920.05%
2207FST Corp.KBSX$1.31-1.13%154$57.53M$0.81 - $1.790.00%
2208Goldman Sachs BDC, Inc.GSBD$8.77-2.18%796.40K$986.67M$8.36 - $10.380.00%
2209Conagra Brands, Inc.CAG$15.30-0.03%8.16M$7.31B$12.53 - $20.320.10%
2210Cartesian Therapeutics, Inc.RNAC$6.87-0.15%114.98K$207.85M$5.60 - $11.000.00%
2211NATURAL GROCERS BY VITAMIN COTTAGE, INC.NGVC$29.06-1.76%79.48K$669.65M$23.47 - $34.590.02%
2212Neuronetics, Inc.STIM$2.46-8.69%1.33M$187.06M$0.80 - $3.440.00%
2213Strattec Security Corp.STRT$59.97-1.84%31.18K$238.96M$57.01 - $93.000.00%
2214Star Equity Holdings, Inc.STRR$9.79+0.77%884$36.12M$8.95 - $11.910.05%
2215ServiceTitan, Inc.TTAN$82.31-6.53%1.01M$8.00B$53.00 - $111.360.00%
2216Sprinklr, Inc.CXM$6.78-1.17%1.20M$888.11M$4.71 - $8.280.00%
2217Mannatech Inc.MTEX$8.13-4.98%54.92K$15.69M$3.80 - $9.970.00%
2218Stifel Financial Corp.SF$71.53-2.25%936.96K$10.80B$65.40 - $89.830.02%
2219Village Farms International, Inc.VFF$2.79-4.95%1.41M$340.57M$1.80 - $4.990.00%
2220Vor Biopharma Inc.VOR$18.79-6.36%386.69K$1.15B$6.50 - $26.000.00%
2221CAMP4 Therapeutics CorporationCAMP$3.74-0.53%101.03K$234.70M$2.90 - $7.750.00%
2222AutoZone, Inc.AZO$3,292.51-1.24%102.45K$52.99B$2,730.65 - $3,996.240.00%
2223Masonglory LimitedFFTT$3.77-1.05%74.73K$13.53M$3.15 - $4.300.00%
2224Caris Life Sciences, Inc.CAI$26.29-21.79%6.37M$9.07B$14.19 - $36.500.00%
2225Disc Medicine, Inc.IRON$79.50-4.37%406.76K$3.05B$40.00 - $99.500.00%
2226JATT III Acquisition Corp.JTTT$10.31-0.34%4.50K$91.25M$10.15 - $11.950.00%
2227Verrica Pharmaceuticals Inc.VRCA$3.11-9.70%115.73K$53.36M$3.10 - $9.820.00%
2228Hess Midstream LPHESM$30.44-4.30%2.00M$3.91B$29.52 - $41.440.09%
2229The Joint Corp.JYNT$7.47-0.59%40.14K$105.59M$6.79 - $10.670.00%
2230Impinj, Inc.PI$162.32-9.65%207.48K$5.01B$87.36 - $215.250.00%
2231Avalyn Pharma Inc.AVLN$26.58-3.20%254.49K$1.13B$22.24 - $40.170.00%
2232Toast, Inc.TOST$35.17-1.10%10.01M$18.08B$22.26 - $39.670.00%
2233China Natural Resources, Inc.CHNR$3.98-0.62%552$4.99M$3.18 - $5.800.00%
2234Biglari Holdings Inc.BH$333.13-10.40%47.79K$703.60M$234.91 - $483.600.00%
2235A2Z Cust2Mate Solutions Corp.AZ$5.89-8.82%876.20K$262.37M$4.97 - $8.720.00%
2236Hercules Capital, Inc.HTGC$16.31-2.22%1.60M$3.09B$13.70 - $19.130.11%
2237CS Disco, Inc.LAW$5.61-2.97%169.10K$364.46M$2.45 - $9.110.00%
2238L3Harris Technologies, Inc.LHX$259.26-0.28%1.71M$48.27B$232.34 - $379.230.02%
2239Oaktree Specialty Lending CorporationOCSL$12.44-1.47%463.19K$1.10B$10.63 - $13.900.12%
2240UFP Industries, Inc.UFPI$82.77-4.65%265.68K$4.57B$73.72 - $118.000.02%
2241Pershing Square USA, Ltd.PSUS$36.98-5.00%680.13K$0$35.71 - $44.000.00%
2242Hubbell IncorporatedHUBB$423.32-3.84%913.89K$22.37B$403.82 - $565.500.00%
2243Abeona Therapeutics Inc.ABEO$3.94-6.87%985.54K$225.59M$3.92 - $7.650.00%
2244Texas Pacific Land CorporationTPL$277.21-3.46%634.89K$19.12B$269.23 - $547.200.01%
2245TTM Technologies Inc.TTMI$63.40-13.16%7.99M$6.68B$55.44 - $223.830.00%
2246CEVA Inc.CEVA$24.65-10.71%621.30K$693.91M$17.02 - $51.600.00%
2247INSTALLED BUILDING PRODUCTS, INC.IBP$222.53-5.59%614.02K$5.91B$176.15 - $349.000.02%
2248Investors Title CoITIC$256.21-5.04%43.19K$483.72M$209.75 - $309.550.04%
2249NexGen Energy Ltd.NXE$7.92-1.00%8.10M$5.30B$7.33 - $13.960.00%
2250Sangoma Technologies CorporationSANG$4.48-1.58%53.68K$149.29M$3.40 - $5.420.00%

Anthropic (PRE): Win NVIDIA H200

Claim PRE points for guaranteed prizes up to $3K

Anthropic (PRE): Win NVIDIA H200

Trade U.S. stocks Your Way on MEXC

RealStocksTokenized StocksStock Futures
What it isRealStocks — real shares of U.S.-listed companiesBlockchain-based tokens linked to U.S. stocks/ETFsUSDT-margined futures on U.S. stock price movements
OwnershipYes — actual sharesNo — synthetic exposure onlyNo — derivative exposure only
Shareholder rightsYes (e.g. dividends)NoNo
Trading hoursU.S. market sessions (pre-market, regular, after-hours, overnight)24/7Up to 24/7 (supported pairs)
Position typesBuy and holdBuy and holdLong, short, leveraged
Best forLong-term investors seeking ownership and dividend incomeTraders wanting round-the-clock access to stock exposure without holding sharesActive/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
Lyell Immunopharma, Inc. (LYEL) currently shows a 52-week decline of 10.70% as of 2026-11-05 20:23 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.