Dow Jones
51,853.69
Change
-1,502.43-2.82%
52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.
Market Overview
U.S. stocks are broadly lower today, with the Dow Jones down 2.82%, the S&P 500 down 3.66%, and the Nasdaq Composite down 4.90%. Market breadth is negative, with 4,629 stocks declining versus 486 advancing, pointing to a broadly bearish bias.
S&P 500
7,406.34
Change
-282.28-3.66%
Nasdaq Composite
24,474.441
Change
-1,262.072-4.90%
24H Gainers
486
24H Losers
4,629
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 4301 | Rein Therapeutics, Inc.RNTX | $0.60 | -8.91% | 126.02K | $51.76M | $0.54 - $2.10 | 0.00% |
| 4302 | Everbright Digital Holding LimitedEDHL | $6.14 | +1.49% | 2.52M | $9.73M | $2.00 - $18.08 | 0.00% |
| 4303 | ProKidney Corp.PROK | $1.01 | -9.82% | 896.14K | $212.11M | $0.87 - $2.95 | 0.00% |
| 4304 | Cognition Therapeutics, Inc.CGTX | $0.64 | -5.59% | 499.77K | $60.38M | $0.55 - $1.82 | 0.00% |
| 4305 | RYTHM, Inc.RYM | $15.74 | -11.30% | 42.25K | $34.31M | $14.00 - $50.38 | 0.00% |
| 4306 | National CineMedia, Inc.NCMI | $1.63 | +3.50% | 299.70K | $152.49M | $1.43 - $4.40 | 0.08% |
| 4307 | Snail, Inc.SNAL | $1.93 | -9.09% | 25.84K | $6.19M | $1.70 - $10.80 | 0.00% |
| 4308 | Veea Inc.VEEA | $4.40 | -1.35% | 68.44K | $13.69M | $1.34 - $16.44 | 0.00% |
| 4309 | WM Technology, Inc.MAPS | $0.00 | 0.00% | 0 | $0 | $0.28 - $1.21 | 0.04% |
| 4310 | Teamshares Inc.TMS | $4.65 | +1.07% | 32.59K | $338.15M | $3.88 - $13.20 | 0.00% |
| 4311 | Solana CompanyHSDT | $1.89 | -9.76% | 415.46K | $114.49M | $1.19 - $5.77 | 0.00% |
| 4312 | BuzzFeed, Inc.BZFD | $0.61 | -38.63% | 1.60M | $50.48M | $0.54 - $2.21 | 0.00% |
| 4313 | PicS N.VPICS | $7.06 | -1.93% | 396.02K | $879.90M | $6.42 - $19.95 | 0.00% |
| 4314 | Fusion Fuel Green PLCHTOO | $1.36 | -19.14% | 12.85K | $10.22M | $1.36 - $5.08 | 0.00% |
| 4315 | Mobilicom LimitedMOB | $2.55 | -14.72% | 84.28K | $39.63M | $2.53 - $9.78 | 0.00% |
| 4316 | HawkEye 360, Inc.HAWK | $12.59 | -4.94% | 993.86K | $1.34B | $11.25 - $35.73 | 0.00% |
| 4317 | GDEV Inc.GDEV | $8.48 | -7.48% | 1.66K | $153.86M | $8.48 - $25.30 | 0.00% |
| 4318 | Proficient Auto Logistics, Inc.PAL | $2.68 | -9.52% | 267.66K | $75.29M | $2.35 - $10.97 | 0.00% |
| 4319 | Energy Recovery, Inc.ERII | $6.38 | -11.85% | 829.32K | $328.91M | $6.25 - $17.36 | 0.00% |
| 4320 | CoreWeave, Inc.CRWV | $42.17 | -12.80% | 53.39M | $27.66B | $40.69 - $138.25 | 0.00% |
| 4321 | Palladyne AI Corp.PDYN | $2.75 | -13.64% | 895.92K | $135.93M | $2.71 - $10.00 | 0.00% |
| 4322 | Arq, Inc.ARQ | $2.34 | +28.38% | 7.52M | $102.05M | $1.54 - $6.49 | 0.00% |
| 4323 | Texxon Holding LimitedNPT | $1.67 | -5.54% | 1.81K | $37.09M | $1.14 - $22.38 | 0.00% |
| 4324 | Alnylam Pharmaceuticals, Inc.ALNY | $159.34 | -1.16% | 1.45M | $21.34B | $156.00 - $479.79 | 0.00% |
| 4325 | QT Imaging Holdings, Inc.QTI | $2.19 | -2.51% | 11.13K | $30.22M | $2.13 - $7.60 | 0.00% |
| 4326 | Aprea Therapeutics, Inc.APRE | $0.48 | -2.61% | 128.70K | $6.04M | $0.41 - $1.49 | 0.00% |
| 4327 | REalloys Inc.ALOY | $5.81 | -11.86% | 1.47M | $404.90M | $5.81 - $26.90 | 0.00% |
| 4328 | ALPS Group Inc.ALPS | $0.32 | +3.57% | 25.36K | $51.37M | $0.23 - $1.72 | 0.00% |
| 4329 | SenesTech, Inc.SNES | $1.17 | +1.65% | 109.69K | $6.35M | $0.55 - $3.61 | 0.00% |
| 4330 | Solidion Technology, Inc.STI | $4.00 | -8.67% | 73.64K | $35.93M | $2.94 - $46.00 | 0.00% |
| 4331 | Medical Properties Trust, Inc.MPT | $1.86 | -9.27% | 12.90M | $1.11B | $1.85 - $6.47 | 0.17% |
| 4332 | Biote Corp.BTMD | $1.06 | -14.63% | 213.71K | $30.40M | $1.00 - $2.98 | 0.04% |
| 4333 | Klarna Group plcKLAR | $13.27 | -4.25% | 3.02M | $5.07B | $12.06 - $38.19 | 0.00% |
| 4334 | BigBear.ai Holdings, Inc.BBAI | $2.21 | -13.28% | 15.72M | $1.07B | $2.07 - $7.40 | 0.00% |
| 4335 | SkinHealth Systems Inc.SKIN | $10.62 | -0.36% | 13.44K | $69.43M | $9.68 - $34.80 | 0.00% |
| 4336 | Atlas Lithium CorporationATLX | $1.58 | -8.09% | 216.46K | $46.60M | $1.52 - $6.72 | 0.00% |
| 4337 | Lucid Diagnostics Inc.LUCD | $0.39 | -11.03% | 1.31M | $79.87M | $0.30 - $1.63 | 0.00% |
| 4338 | Lumen Technologies, Inc.LUMN | $3.92 | -12.30% | 14.20M | $4.04B | $3.85 - $11.43 | 0.00% |
| 4339 | KinderCare Learning Companies, Inc.KLC | $2.02 | -6.07% | 461.46K | $238.81M | $1.63 - $5.90 | 0.00% |
| 4340 | Spruce Biosciences, Inc.SPRB | $43.14 | -6.02% | 35.94K | $123.98M | $38.06 - $129.00 | 0.00% |
| 4341 | Eve Holding, Inc.EVEX | $1.50 | -10.71% | 895.24K | $520.99M | $1.41 - $5.16 | 0.00% |
| 4342 | Oculis Holding AGOCS | $6.91 | -5.29% | 166.72K | $400.67M | $6.79 - $34.48 | 0.00% |
| 4343 | Insight Molecular Diagnostics Inc.IMDX | $2.38 | -10.19% | 71.77K | $77.92M | $2.35 - $8.51 | 0.00% |
| 4344 | Red Cat Holdings, Inc.RCAT | $3.35 | -16.00% | 5.79M | $411.80M | $3.26 - $18.78 | 0.00% |
| 4345 | Plutus Financial Group LimitedPLUT | $1.27 | -1.78% | 9.66K | $19.49M | $1.10 - $3.82 | 0.00% |
| 4346 | SIGA Technologies Inc.SIGA | $3.00 | -4.44% | 208.36K | $215.91M | $2.83 - $8.46 | 0.19% |
| 4347 | Azio AI Holdings, Inc.AZIO | $0.67 | -8.07% | 145.50K | $11.53M | $0.67 - $2.06 | 0.00% |
| 4348 | Addentax Group Corp.ATXG | $2.54 | -5.78% | 41.38K | $3.00M | $2.24 - $9.55 | 0.00% |
| 4349 | Nano Labs LtdNA | $1.46 | -7.01% | 21.02K | $30.13M | $1.35 - $5.16 | 0.00% |
| 4350 | Blend Labs, Inc.BLND | $1.15 | -10.16% | 579.52K | $267.08M | $0.88 - $3.44 | 0.00% |
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RealStocks
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Rein Therapeutics, Inc. (RNTX) currently leads with a 52-week gain of 62.26% as of 2026-11-05 18:02 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.
Discover Top US Stocks
Apple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBV
Apple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDABBVIE INC.ABBV
Nvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COST
Nvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNBroadcom Inc.AVGOWalmart Inc.WMTExxon Mobil CorporationXOMCostco Wholesale Corp.COST
Microsoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVX
Microsoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYMicron Technology, Inc.MUJohnson & JohnsonJNJChevron CorporationCVX
Alphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTR
Alphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTRAlphabet Inc.GOOGLTesla, Inc.TSLABerkshire Hathaway Inc.BRK.AVISA Inc.VMastercard IncorporatedMAPalantir Technologies Inc.PLTR
Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.