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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦2.88%⁩, the S&P 500 down ⁦3.75%⁩, and the Nasdaq Composite down ⁦4.95%⁩. Market breadth is negative, with 4,623 stocks declining versus 492 advancing, pointing to a broadly bearish bias.

Dow Jones
51,818.99
Change
-1,537.13-2.88%
S&P 500
7,400.68
Change
-287.94-3.75%
Nasdaq Composite
24,462.408
Change
-1,274.105-4.95%
24H Gainers
492
24H Losers
4,623

52 Week Gainers

#Stock52 Week Range
4051Passage Bio, Inc.PASG$3.35-4.80%19.77K$10.78M$3.29 - $20.000.00%
4052Veracyte, Inc.VCYT$23.00-56.45%10.00M$1.85B$22.17 - $60.910.00%
4053Pennant Investment Corp.PNNT$3.23+0.15%762.94K$211.23M$2.78 - $6.580.31%
4054Gilat Satellite Networks LtdGILT$6.61-6.52%895.77K$488.17M$6.46 - $20.930.00%
4055GoPro, Inc.GPRO$0.88-6.23%5.96M$139.41M$0.57 - $2.050.00%
4056Walker & Dunlop, Inc.WD$39.77+2.53%503.44K$1.37B$31.40 - $81.110.08%
4057BARK, Inc.BARK$8.05-2.67%13.32K$72.72M$7.39 - $19.800.00%
4058Protara Therapeutics, Inc.TARA$2.21-5.96%369.83K$130.31M$2.21 - $7.820.00%
4059ImageneBio, Inc.IMA$4.08-0.44%5.43K$46.34M$3.88 - $8.840.00%
4060PTL LTDPTLE$9.50-1.15%86.60K$59.23M$4.00 - $20.850.00%
4061iBio, Inc.IBIO$0.71-10.89%472.17K$45.79M$0.69 - $3.820.00%
4062monday.com Ltd.MNDY$94.89-1.92%850.77K$4.85B$57.50 - $194.910.00%
4063Coya Therapeutics, Inc.COYA$2.85-11.69%234.69K$66.74M$2.74 - $6.620.00%
4064BCP Investment CorporationBCIC$5.96-2.16%36.70K$73.74M$5.78 - $13.500.27%
4065Microbot Medical, Inc.MBOT$1.04-8.33%1.22M$70.19M$0.93 - $2.850.00%
4066Quantinuum Inc.QNT$29.72-9.69%2.23M$1.22B$28.35 - $86.790.00%
4067Journey Medical CorporationDERM$4.34-8.25%147.02K$96.56M$4.31 - $9.550.00%
4068ODDITY Tech LtdODD$20.71-4.52%300.01K$716.27M$9.25 - $46.450.00%
4069International Money Express, Inc.IMXI$7.34-10.59%616.70K$221.75M$7.04 - $15.950.00%
4070Pliant Therapeutics, Inc.PLRX$0.80-2.48%168.94K$49.72M$0.80 - $1.810.00%
4071NeoVolta Inc.NEOV$2.04-10.53%654.82K$120.15M$1.36 - $7.130.00%
4072Insulet CorporationPODD$153.74-6.41%625.17K$10.66B$126.40 - $354.880.00%
4073comScore, Inc.SCOR$3.29+1.21%10.65K$50.03M$3.05 - $9.340.00%
4074SITE Centers Corp.SITC$3.63-2.42%1.92M$190.75M$2.80 - $7.490.82%
4075Versus Systems Inc.VS$0.86-5.40%3.31K$5.34M$0.71 - $1.860.00%
4076Cabaletta Bio, Inc.CABA$1.26-10.56%4.46M$214.47M$1.19 - $4.230.00%
4077Webull CorporationBULL$4.82-9.74%6.77M$2.81B$4.50 - $10.370.00%
4078Life360, Inc.LIF$46.20-4.00%222.83K$3.76B$37.01 - $96.660.00%
4079PetMed Express, Inc.PETS$1.22-2.02%30.52K$26.34M$1.15 - $4.100.00%
4080Coherus Oncology, Inc.CHRS$0.76-11.14%1.42M$116.96M$0.73 - $2.620.00%
4081Health Catalyst, Inc.HCAT$1.48-7.86%189.93K$111.00M$0.96 - $3.360.00%
4082Destination XL Group, Inc.DXLG$0.46-4.18%22.90K$25.45M$0.36 - $1.580.00%
4083Optex Systems Holdings, INC.OPXS$8.21-15.77%21.82K$57.11M$7.79 - $17.280.00%
4084Aptiv PLCAPTV$40.29-6.73%1.92M$9.18B$40.02 - $88.930.00%
4085U.S. GoldMining Inc.USGO$4.89-1.29%78.10K$68.63M$4.35 - $17.980.00%
4086WISeQey Corp.WQEY$6.44-10.90%40.90K$41.88M$6.38 - $19.780.00%
4087Mesabi TrustMSB$16.91-4.08%48.11K$221.86M$16.74 - $42.380.06%
4088ADTRAN Holdings, Inc.ADTN$4.04-14.38%2.50M$328.78M$4.03 - $19.980.00%
4089Greenland Technologies Holding CorporationGTEC$0.49-7.15%111.86K$8.52M$0.42 - $1.610.27%
4090CALIX, INC.CALX$32.09-5.07%533.89K$2.02B$31.89 - $68.190.00%
4091CBL International LimitedBANL$2.90-0.89%5.52K$6.15M$2.77 - $16.390.00%
4092CorMedix Inc.CRMD$5.29-5.83%971.74K$412.72M$5.29 - $13.020.00%
4093Papa John's International Inc.PZZA$19.57-2.00%1.54M$644.18M$17.70 - $48.830.10%
4094Reddit, Inc.RDDT$93.04-8.40%4.13M$13.67B$89.28 - $263.500.00%
4095P3 Health Partners Inc.PIII$3.99+3.94%3.81K$16.01M$1.52 - $16.890.00%
4096Hudson Technologies Inc.HDSN$4.09-6.80%412.92K$171.97M$4.04 - $8.790.00%
4097Curanex Pharmaceuticals Inc.CURX$5.64-1.64%5.37K$9.17M$3.58 - $13.350.00%
4098Kailera Therapeutics, Inc.KLRA$12.30-3.71%331.10K$1.58B$9.76 - $28.230.00%
4099Eagle Nuclear Energy Corp.NUCL$4.09-2.16%186.09K$130.61M$3.91 - $14.220.00%
4100FreightCar America, Inc.RAIL$4.07-3.10%131.94K$133.46M$3.85 - $14.900.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Passage Bio, Inc. (PASG) currently leads with a 52-week gain of 49.99% as of 2026-11-05 18:30 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.