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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦2.92%⁩, the S&P 500 down ⁦3.75%⁩, and the Nasdaq Composite down ⁦4.82%⁩. Market breadth is negative, with 4,627 stocks declining versus 488 advancing, pointing to a broadly bearish bias.

Dow Jones
51,796.2
Change
-1,559.92-2.92%
S&P 500
7,400.2
Change
-288.42-3.75%
Nasdaq Composite
24,496.051
Change
-1,240.462-4.82%
24H Gainers
488
24H Losers
4,627

52 Week Gainers

#Stock52 Week Range
3501Spectral AI, Inc.MDAI$1.41-5.88%396.46K$45.38M$1.18 - $2.970.00%
3502CION Investment CorporationCION$6.51-8.30%890.86K$320.56M$5.83 - $10.400.20%
3503Alaunos Therapeutics, Inc.TCRT$1.79-2.22%42.25K$5.93M$0.72 - $4.500.00%
3504Lennox International Inc.LII$349.29-2.85%530.14K$11.95B$322.00 - $587.270.02%
3505Educational Development Corp.EDUC$1.00-2.86%20.51K$8.57M$0.98 - $1.650.00%
3506Conduent IncorporatedCNDT$1.65+0.61%710.99K$255.83M$1.15 - $2.360.03%
3507Cadre Holdings, Inc.CDRE$32.09+3.68%357.22K$1.37B$24.07 - $48.760.01%
3508POET Technologies Inc.POET$4.29-12.91%10.13M$659.18M$3.87 - $20.810.00%
3509EMPIRE STATE REALTY TRUST, INC.ESRT$5.18-1.61%1.98M$892.68M$3.93 - $7.540.03%
3510Viking Therapeutics, Inc.VKTX$25.92-8.04%3.11M$3.31B$23.82 - $43.150.00%
3511Afya LimitedAFYA$10.18-3.10%143.88K$487.92M$9.66 - $16.160.00%
3512Hawaiian Electric Industries, Inc.HE$8.26-3.35%2.42M$1.43B$8.14 - $17.380.00%
3513Perella Weinberg PartnersPWP$13.40-8.14%938.59K$1.09B$12.13 - $25.930.03%
3514MGP Ingredients Inc.MGPI$17.14-0.61%303.64K$367.19M$12.42 - $26.620.03%
3515Amplify Energy Corp.AMPY$3.25-7.18%817.94K$134.53M$3.21 - $6.790.00%
3516AdaptHealth Corp.AHCO$7.34+0.27%3.11M$1.00B$5.21 - $13.430.00%
3517Oric Pharmaceuticals, Inc.ORIC$8.79-6.00%677.92K$911.00M$7.23 - $14.680.00%
3518Kura Oncology, Inc.KURA$7.05-8.21%2.22M$627.62M$6.97 - $13.900.00%
3519ADARx Pharmaceuticals, Inc.ADRX$13.72-8.29%514.36K$1.68B$12.76 - $23.210.00%
3520First Solar, Inc.FSLR$196.59-0.25%4.81M$21.13B$165.86 - $320.950.00%
3521Patriot National Bancorp Inc.PNBK$0.83-3.80%180.75K$98.44M$0.80 - $2.000.00%
3522Strive, Inc.ASST$20.68-10.56%7.74M$1.56B$7.02 - $34.400.01%
3523Universal Technical Institute, Inc.UTI$19.91-11.24%1.10M$1.10B$18.02 - $51.340.00%
3524Five Point Holdings, LLCFPH$4.29-7.11%144.45K$308.18M$4.02 - $6.470.03%
3525C3.ai, Inc.AI$11.36-5.56%3.44M$1.79B$7.67 - $17.450.00%
3526Sunrise Realty Trust, Inc.SUNS$6.68-4.67%62.13K$90.34M$5.77 - $10.450.00%
3527FinWise Bancorp CommonFINW$13.56+1.17%34.07K$188.32M$9.58 - $19.860.00%
3528Xilio Therapeutics, Inc.XLO$8.06-4.56%9.91K$53.07M$6.47 - $11.900.00%
3529Nature's Sunshine Products Inc.NATR$9.97-23.91%1.24M$175.52M$9.44 - $28.140.00%
3530Champions Oncology, Inc.CSBR$4.80-0.21%9.11K$66.81M$4.59 - $8.310.00%
3531TaskUs, Inc.TASK$8.98+3.65%453.59K$329.34M$4.46 - $13.720.44%
3532Quest Resource Holding CorporationQRHC$0.98-7.11%9.22K$20.69M$0.81 - $2.410.00%
3533Air Global PLCAIIR$7.37+0.34%11.46K$1.16B$5.29 - $13.370.00%
3534IPG Photonics CorporationIPGP$62.73-10.56%323.68K$2.67B$61.94 - $155.820.00%
3535Rush Street Interactive, Inc.RSI$11.72-5.02%3.29M$1.35B$11.39 - $34.530.00%
3536Snap Inc.SNAP$5.14-14.10%54.90M$7.39B$3.81 - $9.130.00%
3537Aviat Networks, Inc.AVNW$17.11-13.09%111.32K$220.06M$13.92 - $27.020.00%
3538Lightwave Logic, Inc.LWLG$3.85-11.05%4.45M$592.77M$2.84 - $18.710.00%
3539Immatics N.V.IMTX$6.29-8.90%719.63K$859.78M$6.16 - $12.410.00%
3540Collegium Pharmaceutical, Inc.COLL$25.20+7.27%898.93K$820.50M$21.43 - $50.790.00%
3541Qwest CorporationCTHH$13.34-4.05%27.95K$0$13.27 - $19.150.00%
3542Recursion Pharmaceuticals, Inc.RXRX$3.48-10.95%18.28M$1.86B$2.77 - $5.240.00%
3543EpicQuest Education Group International LimitedEEIQ$4.11-6.92%1.24K$6.77M$1.90 - $12.700.00%
3544HUB Group Inc.HUBG$24.99-7.07%337.94K$1.51B$24.95 - $53.260.02%
3545Madison Air Solutions CorporationMAIR$22.19-7.45%3.10M$11.67B$21.35 - $44.500.00%
3546Stewart Information Services CorporationSTC$48.20+2.91%307.92K$1.47B$42.66 - $78.610.05%
3547Unisys CorporationUIS$2.35+0.43%1.88M$171.72M$1.97 - $4.980.00%
3548Grand Canyon Education, Inc.LOPE$124.53-16.71%747.39K$3.25B$121.67 - $187.100.00%
3549ESAB CorporationESAB$78.56-0.23%618.14K$4.88B$62.74 - $137.420.01%
3550Mobile Infrastructure CorporationBEEP$2.40+1.91%5.66K$98.91M$1.29 - $3.520.01%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Spectral AI, Inc. (MDAI) currently leads with a 52-week gain of 28.43% as of 2026-11-05 19:43 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.