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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦2.19%⁩, the S&P 500 down ⁦2.91%⁩, and the Nasdaq Composite down ⁦4.05%⁩. Market breadth is negative, with 4,331 stocks declining versus 784 advancing, pointing to a broadly bearish bias.

Dow Jones
52,185.17
Change
-1,170.95-2.19%
S&P 500
7,464.95
Change
-223.67-2.91%
Nasdaq Composite
24,694.839
Change
-1,041.674-4.05%
24H Gainers
784
24H Losers
4,331

52 Week Gainers

#Stock52 Week Range
451Vaxcyte, Inc.PCVX$63.20-3.26%429.74K$9.40B$39.87 - $90.750.00%
452Stepan Co.SCL$68.73-2.40%35.91K$1.56B$42.14 - $72.670.02%
453Lattice Semiconductor Corp.LSCC$98.85-7.02%781.58K$13.54B$60.50 - $157.010.00%
454ManpowerGroupMAN$46.61-0.53%120.64K$2.17B$25.15 - $63.880.03%
455Aclaris Therapeutics, Inc.ACRS$3.54-3.80%725.03K$494.28M$2.10 - $6.600.00%
456The Gorman-Rupp CompanyGRC$70.93-3.48%55.80K$1.87B$42.31 - $92.780.01%
457Toronto Dominion BankTD$126.00-1.63%386.52K$205.29B$79.52 - $129.100.00%
458Humana Inc.HUM$413.52-0.33%483.86K$49.66B$163.11 - $456.500.01%
459Alpha Teknova, Inc.TKNO$7.72+6.85%624.23K$414.85M$1.91 - $9.480.00%
460Canadian Natural Resources LimitedCNQ$49.74+0.46%3.53M$102.22B$30.13 - $56.270.00%
461Hasbro, Inc.HAS$119.92-0.62%672.63K$16.77B$74.78 - $124.030.02%
462Five Below, Inc.FIVE$243.03-3.10%189.97K$13.38B$143.02 - $263.880.00%
463Plains GP Holdings, L.PPAGP$26.79-0.48%688.25K$5.30B$16.89 - $28.960.06%
464Origin Bancorp, Inc.OBK$55.25-1.85%35.26K$0$32.28 - $58.050.01%
465Precision Drilling CorporationPDS$89.78-1.38%51.25K$1.13B$56.10 - $112.030.00%
466Varex Imaging CorporationVREX$18.45-0.30%272.67K$776.96M$9.09 - $18.630.00%
467Tower Semiconductor LtdTSEM$135.34-8.21%2.89M$17.63B$80.63 - $319.940.00%
468HBT Financial, Inc.HBT$37.34+1.19%30.84K$1.36B$22.37 - $38.620.02%
469Hafnia LimitedHAFN$9.60-1.43%808.65K$5.46B$5.17 - $11.120.00%
470Richardson Electronics LtdRELL$16.94-12.91%198.65K$217.54M$9.37 - $23.150.01%
471MacroGenics, Inc.MGNX$2.23-0.87%469.40K$142.37M$1.29 - $5.080.00%
472Fidelity D & D Bancorp, Inc.FDBC$69.22+0.54%4.76K$402.06M$41.00 - $71.960.02%
473Heartflow, Inc.HTFL$53.86-2.97%475.63K$4.74B$20.13 - $60.560.00%
474Orion Energy Systems, Inc.OESX$12.95-31.58%64.70K$52.97M$8.35 - $31.650.00%
475Citizens Financial Services, Inc.CZFS$87.45-1.18%7.91K$420.62M$53.14 - $88.750.02%
476Orange County Bancorp, Inc.OBT$40.20-2.03%14.00K$538.99M$25.01 - $41.660.02%
477Hooker Furnishings CorporationHOFT$14.42-6.34%23.03K$154.14M$8.88 - $18.090.04%
478James Hardie Industries plcJHX$28.67-2.91%3.68M$16.64B$16.46 - $31.430.00%
479Reliance, Inc.RS$428.57-2.16%124.31K$21.83B$263.12 - $454.930.00%
480Solid Biosciences Inc.SLDB$6.09-5.37%467.73K$652.57M$3.79 - $11.450.00%
481Applied Optoelectronics, Inc.AAOI$48.73-15.29%12.87M$4.12B$18.50 - $233.670.00%
482Rackspace Technology, Inc.RXT$2.40-13.88%2.66M$610.42M$0.39 - $8.600.00%
483Safe Bulkers, Inc.SB$7.26-0.95%317.10K$738.90M$4.58 - $9.310.00%
484Krystal Biotech, Inc.KRYS$308.42-0.46%71.04K$9.13B$192.52 - $382.540.00%
485Cohu Inc.COHU$37.06-13.64%1.26M$1.75B$21.10 - $75.720.00%
486BRC Group Holdings, Inc.RILYT$18.98-2.40%14.96K$0$10.35 - $22.200.00%
487Host Hotels & Resorts, Inc.HST$24.90-4.33%8.32M$17.06B$16.02 - $26.440.04%
488Ducommun IncorporatedDCO$141.09-8.03%171.18K$2.13B$84.76 - $210.390.00%
489Pharvaris N.V.PHVS$33.34-2.33%356.50K$2.18B$21.02 - $43.250.00%
490Etsy, Inc.ETSY$92.42-3.76%1.77M$7.97B$44.00 - $97.850.00%
491Clover Health Investments, Corp.CLOV$4.55-1.60%4.64M$1.98B$1.58 - $5.590.00%
492Myers Industries, Inc.MYE$27.32-4.00%55.13K$1.03B$16.66 - $37.450.02%
493FIVE9, INC.FIVN$34.86-3.43%520.93K$2.67B$13.29 - $40.000.00%
494Kronos Worldwide, Inc.KRO$7.25-5.30%118.22K$833.88M$4.08 - $9.170.03%
495W.W. Grainger, Inc.GWW$1,473.39-0.72%147.51K$69.40B$906.52 - $1,521.410.01%
496Venture Global, Inc.VG$11.86-1.37%6.95M$32.18B$5.72 - $17.620.01%
497Design Therapeutics, Inc.DSGN$10.03-5.08%144.55K$627.38M$6.23 - $17.250.00%
498J.Jill, Inc.JILL$23.01-2.16%67.68K$342.06M$10.40 - $25.140.02%
499Twilio Inc.TWLO$200.89-5.26%1.86M$30.85B$105.00 - $308.400.00%
500Cronos Group Inc.CRON$3.75+7.83%2.41M$1.38B$2.28 - $3.900.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Vaxcyte, Inc. (PCVX) currently leads with a 52-week gain of 56.75% as of 2026-11-05 16:55 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.